Article
Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae.
PLoS genetics - 1 Oct 2013
Yin Yi, Petes Thomas D
Abstract excerpt
In the yeast Saccharomyces cerevisiae and most other eukaryotes, mitotic recombination is important for the repair of double-stranded DNA breaks (DSBs). Mitotic recombination between homologous chromosomes can result in loss of heterozygosity (LOH). In this study, LOH events induced by ultraviolet (UV) light are mapped throughout the genome to a resolution of about 1 kb using single-nucleotide polymorphism (SNP)...
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