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Article

Characterization of meiotic crossovers and gene conversion by whole-genome sequencing in Saccharomyces cerevisiae.

BMC genomics - 15 Oct 2009

Qi Ji, Wijeratne Asela J, Tomsho Lynn P, Hu Yi, Schuster Stephan C, Ma Hong

Abstract excerpt

BACKGROUND: Meiotic recombination alters frequency and distribution of genetic variation, impacting genetics and evolution. In the budding yeast, DNA double strand breaks (DSBs) and D loops form either crossovers (COs) or non-crossovers (NCOs), which occur at many sites in the genome. Differences at the nucleotide level associated with COs and NCOs enable us to detect these recombination events and their...

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Identifiers

PMID: 19832984
DOI: 10.1186/1471-2164-10-475
PMCID: PMC2770529

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