Article

A genome-wide screen for genes affecting spontaneous direct-repeat recombination in <i>Saccharomyces cerevisiae</i>

2020-02-11

Abstract excerpt

<h4>ABSTRACT</h4> Homologous recombination is an important mechanism for genome integrity maintenance, and several homologous recombination genes are mutated in various cancers and cancer-prone syndromes. However, since in some cases homologous recombination can lead to mutagenic outcomes, this pathway must be tightly regulated, and mitotic hyper-recombination is a hallmark of genomic instability. We performed tw...

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Literature Corpus work: 4e3c569c-9e53-57b4-b8b4-6d9e0d6eeb66
DOI: 10.1101/2020.02.11.943795

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