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Article

High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human Cells

2022-12-19

Abstract excerpt

<h4>Summary</h4> Viruses encode transcriptional regulatory proteins critical for controlling viral and host gene expression. Given their multifunctional nature and high sequence divergence, it is unclear which viral proteins can affect transcription and which specific sequences contribute to this function. Using a high-throughput assay, we measured the transcriptional regulatory potential of over 60,000 protein t...

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Identifiers and source

Literature Corpus work
ab2ada43-d8c7-5649-8dab-2a1742db43c9
DOI
10.1101/2022.12.16.520835
Open publication

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High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human CellsDOI 10.1101/2022.12.16.520835
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