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Viral transcriptional regulators extensively rewire host pathways through diverse mechanisms

2025-12-02

Abstract excerpt

<h4>Summary</h4> Viral transcriptional regulators (vTRs) reprogram host gene regulatory networks to promote replication, persistence, and immune evasion. Despite the identification of hundreds of vTRs in human viruses, how they rewire host pathways remains unclear. Here, we systematically profiled 95 vTRs from diverse human viruses across multiple functional assays. vTRs perturb immune, cell proliferation/death,...

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Literature Corpus work
ff8ecacc-7f1c-5e64-9f61-5d15c266bf05
DOI
10.64898/2025.12.01.691387
Open publication

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Viral transcriptional regulators extensively rewire host pathways through diverse mechanismsDOI 10.64898/2025.12.01.691387
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