Article

Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types

2023-03-06

Abstract excerpt

<h4>ABSTRACT</h4> The human genome contains millions of candidate cis -regulatory elements (CREs) with cell-type-specific activities that shape both health and myriad disease states. However, we lack a functional understanding of the sequence features that control the activity and cell-type-specific features of these CREs. Here, we used lentivirus-based massively parallel reporter assays (lentiMPRAs) to test the...

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Literature Corpus work: c03c79a5-3d06-5391-a28e-3b34c9c09bb4
DOI: 10.1101/2023.03.05.531189

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