Article

From enhancers to genome conformation: complex transcriptional control underlies expression of a single herpesviral gene

2023-07-08

Abstract excerpt

Complex transcriptional control is a conserved feature of both eukaryotes and the viruses that infect them. Here, we illustrate this by combining high-density functional genomics, expression profiling, and viral-specific chromosome conformation capture to define with unprecedented detail the transcriptional regulation of a single gene, ORF68, from Kaposi’s sarcoma-associated herpesvirus (KSHV). We first identified...

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Literature Corpus work: 15757b88-9dc0-5ca8-bb30-0f57a598c213
DOI: 10.1101/2023.07.08.548212

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