Back to search

Article

Global cis-regulatory landscape of double-stranded DNA viruses

2025-07-20

Abstract excerpt

Most double-stranded DNA (dsDNA) viruses use the host transcriptional machinery to express viral genes for replication and immune evasion. This is mediated by viral cis-regulatory elements (CREs) regulated by host and viral transcription factors (TFs). Although some viral CREs and their regulatory mechanisms have been determined, most remain unidentified. Here, we used massively parallel reporter assays to identif...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cdab2ac8-c497-5a70-8d46-d3eb284e4850
DOI
10.1101/2025.07.20.665756
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Global cis-regulatory landscape of double-stranded DNA virusesDOI 10.1101/2025.07.20.665756
Massively parallel characterization of transcriptional regulatory elements in three diverse human cell typesSemantic proximity
Viral transcriptional regulators extensively rewire host pathways through diverse mechanismsSemantic proximity
High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human CellsSemantic proximity
From enhancers to genome conformation: complex transcriptional control underlies expression of a single herpesviral geneSemantic proximity
Oncogenic Viruses and the Epigenome: How Viruses Hijack Epigenetic Mechanisms to Drive CancerSemantic proximity
A Two-tiered Functional Screen Identifies Herpesviral Transcriptional Modifiers and their Essential DomainsSemantic proximity
Innate Sensing of DNA Virus GenomesSemantic proximity
The logic of DNA replication in double-stranded DNA viruses: insights from global analysis of viral genomesSemantic proximity
Oncoviruses: How do they hijack their host and current treatment regimesSemantic proximity
Diversity and evolution of chromatin proteins encoded by DNA virusesSemantic proximity
Atlas of HIV cis-regulatory elements reveals extensive transcriptional variation across clades, isolates, and within individualsSemantic proximity
ViMIC: A Database of Human Disease-related Virus Mutations, Integration Sites and Cis-effectsSemantic proximity
Select a neighboring publication to make it the new centre.