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Niche-level immune evasion in <i>TP53</i> mutant AML residual disease revealed by spatial proteomics

2026-05-19

Abstract excerpt

<h4>ABSTRACT</h4> Measurable (or minimal) residual disease (MRD) predicts relapse in patients with acute myeloid leukemia (AML). However, the biological and spatial characteristics of the AML bone marrow (BM) microenvironment (BMME) in which MRD cells survive remain largely unexplored; in particular, little is known of the BMME in TP53 mutant ( TP53 mut ) AML. Here, we applied sequential immunofluorescence to w...

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Literature Corpus work
aae93cd6-1e16-554f-8bd3-816d13f97294
DOI
10.64898/2026.05.15.725421
Open publication

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Niche-level immune evasion in <i>TP53</i> mutant AML residual disease revealed by spatial proteomicsDOI 10.64898/2026.05.15.725421
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