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Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular Therapy

2024-02-12

Abstract excerpt

<h4>Summary</h4> Understanding how intra-tumoral immune populations coordinate to generate anti-tumor responses following therapy can guide precise treatment prioritization. We performed systematic dissection of an established adoptive cellular therapy, donor lymphocyte infusion (DLI), by analyzing 348,905 single-cell transcriptomes from 74 longitudinal bone-marrow samples of 25 patients with relapsed myeloid leu...

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Literature Corpus work
41e7b7a7-47ae-5411-a561-570afb99f847
DOI
10.1101/2024.02.09.579677
Open publication

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Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular TherapyDOI 10.1101/2024.02.09.579677
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