Article

Multimodal Spatial Proteomic Profiling in Acute Myeloid Leukemia

2024-08-30

Abstract excerpt

Acute myeloid leukemia (AML) resides in an immune rich microenvironment, yet, immune-based therapies have faltered in eliciting durable responses. Bridging this paradox requires a comprehensive understanding of leukemic interactions within the bone marrow microenvironment. We optimized a high-throughput tissue-microarray based pipeline for high-plex spatial immunofluorescence and mass cytometry imaging on a single...

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Literature Corpus work: cc688ae2-4444-5011-b635-f422e3d61549
DOI: 10.1101/2024.08.30.610347

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