Article

A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia

2023-03-06

Abstract excerpt

Because of the low mutational burden and consequently, fewer potential neoantigens, children with acute myeloid leukemia (AML) are thought to have a T cell-depleted or ‘cold’ tumor microenvironment and may have a low likelihood of response to T cell-directed immunotherapies. Understanding the composition, phenotype, and spatial organization of T cells and other microenvironmental populations in the pediatric AML b...

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Literature Corpus work: 86a28053-dcfe-5d1c-9a89-53916f2d1a1d
DOI: 10.1101/2023.03.03.23286485

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