Article

SIRPα+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function

2024-09-19

Abstract excerpt

Acute myeloid leukemia (AML) continues to have a poor prognosis due to its ability to relapse following initial response to chemotherapy. While immunotherapies hold the promise to revolutionize cancer treatment, AML has been particularly challenging to target. It is therefore important to better understand the relationship between AML cells and immune cells within the bone marrow (BM) microenvironment, where this...

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Literature Corpus work: 366a5fcf-df83-5165-bbf8-fb720b9ad177
DOI: 10.1101/2024.09.15.613123

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