Article

Genetic determinants of <i>EGFR</i> -Driven Lung Cancer Growth and Therapeutic Response <i>In Vivo</i>

2020-04-13

Abstract excerpt

Cancer genome sequencing has uncovered substantial complexity in the mutational landscape of tumors. Given this complexity, experimental approaches are necessary to establish the impact of combinations of genetic alterations on tumor biology and to uncover genotype-dependent effects on drug sensitivity. In lung adenocarcinoma, EGFR mutations co-occur with many putative tumor suppressor gene alterations, however t...

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Literature Corpus work: a85b1139-1e43-5579-8d15-310ca23581c0
DOI: 10.1101/2020.04.13.036921

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