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Article

Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth

2021-09-17

Abstract excerpt

<title>Abstract</title> <p>Oncogenic KRAS mutations occur in approximately 30% of lung adenocarcinoma. Despite several decades of effort, oncogenic KRAS-driven lung cancer remains difficult to treat, and our understanding of the positive and negative regulators of RAS signaling is incomplete. To uncover the functional impact of diverse KRAS-interacting proteins on lung cancer growth in vivo, we used multiplexed s...

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Literature Corpus work
6d983316-6d41-5073-8468-629eaceea9bb
DOI
10.21203/rs.3.rs-900548/v1
Open publication

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Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growthDOI 10.21203/rs.3.rs-900548/v1
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