Article

<i>SMARCA4, STK11,</i> and <i>KEAP1</i> co-inactivation associates with poor prognosis and upregulation of the TGF-β pathway in lung adenocarcinoma

2026-06-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Lung adenocarcinoma (LUAD) is clinically and molecularly defined by oncogenic driver mutations, identification of which has led to the development of driver-targeted therapies and substantial improvements in prognosis for subsets of LUAD patients. Recent studies assessing clinical outcomes in the context of multigenic alterations have identified secondary mutations that migh...

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Literature Corpus work: cf4d6235-802b-5a3e-8a22-34526e135085
DOI: 10.64898/2026.06.03.729911

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