Article

A method for phylogenetic reconstruction of aneuploid cancers based on multiregional genotyping data

2021-01-22

Abstract excerpt

<title>Abstract</title> <p>Phylogenetic reconstruction of cancer cell populations remains challenging. There is a particular lack of tools that deconvolve clones based on copy number aberration analyses of multiple tumor biopsies separated in time and space from the same patient. This has hampered investigations of tumors rich in aneuploidy but few point mutations, as in many childhood cancers. Here, we present D...

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Literature Corpus work: a73f21f1-3d1a-5781-b03b-574f573c9b69
DOI: 10.21203/rs.3.rs-140537/v1

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