Article

Synchronous 3D patterning of diverse CNS progenitors generates motor neurons of broad axial identity

2024-12-17

Abstract excerpt

In vitro human organoid models have become transformative tools for studying organogenesis, enabling the generation of spinal cord organoids (SCOs) that mimic aspects of spinal cord biology. However, current models do not produce spinal motor neurons (spMNs) with a wide range of axial identities along spinal cord segments within a single structure, limiting their utility in understanding human neural axial specifi...

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Literature Corpus work: d99a5804-6cec-5549-b457-f8c911a6cc8c
DOI: 10.1101/2024.12.13.628384

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