Article

Derivation of axioloids, an in vitro model of somitogenesis and axial development from human pluripotent stem cells

2023-02-02

Abstract excerpt

<title>Abstract</title> <p>Here we describe a step-by-step protocol for the derivation of axioloids, a pluripotent stem cell (PSC)-based 3D <italic>in vitro </italic>model of human segmentation and somitogenesis. Mesoderm-based axioloids capture reproducibly core features of the segmentation process <italic>in vitro </italic>including axial elongation, sequential formation of properly patterned epithelial somites...

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Literature Corpus work: 0fccf2e3-eada-5118-94f9-293aa3a7439d
DOI: 10.21203/rs.3.pex-2114/v1

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