Article

In vitro spatiotemporal reconstruction of human skeletal muscle organogenesis

2024-05-12

Abstract excerpt

<h4>Summary</h4> Spatiotemporal recapitulation of long-range trajectories for lineages that influence body patterning along the medio-lateral and proximal-distal axes during embryogenesis in an in vitro system remains elusive. Here we introduce a three-dimensional organoid approach, termed Gastruloids-Lateraloid-Musculoids (GLMs), to model human neural crest, lateral plate mesoderm and skeletal muscle lineage de...

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Literature Corpus work: 854191b1-7c3d-5d03-92a2-57e08abb35f6
DOI: 10.1101/2024.05.10.593520

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