Article

Stochastic Evolutionary Control in Heterogeneous Populations

2026-03-13

Abstract excerpt

<h4>ABSTRACT</h4> Therapeutic resistance, which poses a central challenge in cancer and infectious disease treatment, arises from the evolutionary dynamics of heterogeneous populations as a natural consequence of the evolutionary tendency towards higher fitness. Here we introduce SHEPHERD (Stochastic Heterogeneity–informed Evolutionary Policy Hampering the Expansion of Resistance to Drugs), which integrates Wrigh...

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Literature Corpus work: a6a09b08-b667-56a7-b56e-c2ad8a6d2952
DOI: 10.64898/2026.03.12.711493

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