Article

Drug-induced resistance evolution necessitates less aggressive treatment

2020-10-08

Abstract excerpt

Evolution of drug resistance to anticancer, antimicrobial and antiviral therapies is widespread among cancer and pathogen cell populations. Classical theory posits strictly that genetic and phenotypic variation is generated in evolving populations independently of the selection pressure. However, recent experimental findings among antimicrobial agents, traditional cytotoxic chemotherapies and targeted cancer thera...

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Literature Corpus work: b24cc97c-885d-55d3-98a2-6c8543f6de9c
DOI: 10.1101/2020.10.07.330134

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