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Article

Conceptualizing a tool to optimize therapy based on dynamic heterogeneity.

Physical biology - 1 Dec 2012

Liao David, Estévez-Salmerón Luis, Tlsty Thea D

Abstract excerpt

Complex biological systems often display a randomness paralleled in processes studied in fundamental physics. This simple stochasticity emerges owing to the complexity of the system and underlies a fundamental aspect of biology called phenotypic stochasticity. Ongoing stochastic fluctuations in phenotype at the single-unit level can contribute to two emergent population phenotypes. Phenotypic stochasticity not...

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Identifiers

PMID: 23197078
DOI: 10.1088/1478-3975/9/6/065005
PMCID: PMC3618714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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