Article

Phenotypic Heterogeneity Facilitates Survival While Hindering the Evolution of Drug Resistance Due to Intraspecific Competition

2021-09-20

Abstract excerpt

<h4>ABSTRACT</h4> Rising rates of resistance to antimicrobial drugs threatens the effective treatment of infections across the globe. Drug resistance has been established to emerge from non-genetic mechanisms, such as “persistence” in quiescent microbes and fluctuations in gene expression in actively replicating cells, as well as from genetic mutations. However, it is still unclear how non-genetic drug resistance...

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Literature Corpus work: 05d1ed4d-56c6-529f-b832-963509134b8e
DOI: 10.1101/2021.09.20.460867

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