Article

LABRAT reveals association of alternative polyadenylation with transcript localization, RNA binding protein expression, transcription speed, and cancer survival

2020-10-07

Abstract excerpt

<h4>ABSTRACT</h4> The sequence content of the 3′ UTRs of many mRNA transcripts is regulated through alternative polyadenylation (APA). The study of this process using RNAseq data, though, has been historically challenging. To combat this problem, we developed LABRAT, an APA quantification method. LABRAT takes advantage of newly developed transcriptome quantification techniques to accurately determine relative APA...

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Literature Corpus work: a5d53c6b-66ea-5bb5-a352-a8ccc92cf0d7
DOI: 10.1101/2020.10.05.326702

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