Article

Analyses of Mutational Patterns Induced by Formaldehyde and Acetaldehyde Reveal Similarity to a Common Mutational Signature

2022-03-08

Abstract excerpt

Formaldehyde (CH 2 O) and acetaldehyde (C 2 H 4 O) are reactive small molecules produced endogenously in cells as well as being environmental contaminants. Both of these small aldehydes are classified as human carcinogens, since they are known to damage DNA and exposure is linked to cancer incidence. However, the mutagenic properties of formaldehyde and acetaldehyde remain incompletely understood, at least in p...

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Literature Corpus work: a5bef98e-15c9-5501-98e5-89e09b816b84
DOI: 10.1101/2022.03.08.483495

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