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Article

Homologous recombination contributes to the repair of acetaldehyde-induced DNA damage.

Cell cycle (Georgetown, Tex.) - 1 Feb 2024

Yamazaki Kosuke, Iguchi Tomohiro, Kanoh Yutaka, Takayasu Kazuto, Ngo Trinh Thi To, Onuki Ayaka, Kawaji Hideya, Oshima Shunji, Kanda Tomomasa, Masai Hisao, Sasanuma Hiroyuki

Abstract excerpt

Acetaldehyde, a chemical that can cause DNA damage and contribute to cancer, is prevalently present in our environment, e.g. in alcohol, tobacco, and food. Although aldehyde potentially promotes crosslinking reactions among biological substances including DNA, RNA, and protein, it remains unclear what types of DNA damage are caused by acetaldehyde and how they are repaired. In this study, we explored mechanisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38571319
DOI: 10.1080/15384101.2024.2335028
PMCID: PMC11174073

Genes

TDP1
RAD51
TDP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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