Article

Arp2/3 Complex Activity Enables Nuclear YAP for Naïve Pluripotency of Human Embryonic Stem Cells

2023-01-16

Abstract excerpt

Our understanding of transitions of human embryonic stem cells between distinct stages of pluripotency relies predominantly on regulation by transcriptional and epigenetic programs with limited insight on the role of established morphological changes. We report remodeling of the actin cytoskeleton of human embryonic stem cells (hESCs) as they transition from primed to naïve pluripotency that includes assembly of a...

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Literature Corpus work: a46dfbf9-e131-5fa3-8674-77a5ae5a3e1b
DOI: 10.1101/2023.01.16.524285

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