Article

MethNet: a robust approach to identify regulatory hubs and their distal targets in cancer

2023-07-31

Abstract excerpt

<title>Abstract</title> <p>Aberrations in the capacity of DNA/chromatin modifiers and transcription factors to bind non-coding regions can lead to changes in gene regulation and impact disease phenotypes. However, identifying distal regulatory elements and connecting them with their target genes remains challenging. Here, we present MethNet, a pipeline that integrates large-scale DNA methylation and gene expressi...

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Literature Corpus work: a42a3510-2ee4-503d-aa7f-71f2893c42ca
DOI: 10.21203/rs.3.rs-3150386/v1

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