Article

HemaCisDB: An Interactive Database for Analyzing Cis-Regulatory Elements Across Hematopoietic Malignancies

2024-03-13

Abstract excerpt

Noncoding cis-regulatory elements (CREs), such as transcriptional enhancers, are key regulators of gene expression programs. Accessible chromatin and H3K27ac are well-recognized markers for CREs associated with their biological function. Deregulation of CREs is commonly found in hematopoietic malignancies yet the extent to which CRE dysfunction contributes to pathophysiology remains incompletely understood. Here,...

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Literature Corpus work: 9fab4515-fa3e-511f-b5c9-35b188865b7c
DOI: 10.1101/2024.03.12.583848

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