Article

Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters

2019-04-29

Abstract excerpt

Identifying DNA cis-regulatory modules (CRMs) that control the expression of specific genes is crucial for deciphering the logic of transcriptional control. Natural genetic variation can point to the possible gene regulatory function of specific sequences through their allelic associations with gene expression. However, comprehensive identification of causal regulatory sequences in brute-force association testing...

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Literature Corpus work: fc12b68e-210a-59c5-a270-22a23faddd3b
DOI: 10.1101/620062

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