Article

Accurate prediction of <i>cis</i> -regulatory modules reveals a prevalent regulatory genome of humans

2020-05-16

Abstract excerpt

Annotating all cis -regulatory modules (CRMs) and transcription factor (TF) binding sites(TFBSs) in genomes remains challenging. We tackled the task by integrating putative TFBSs motifs found in available 6,092 datasets covering 77.47% of the human genome. This approach enabled us to partition the covered genome regions into a CRM candidate (CRMC) set (56.84%) and a non-CRMC set (43.16%). Intriguingly, like known...

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Literature Corpus work: 1c142224-e1a8-5b5c-b115-cee2ea3f7a8b
DOI: 10.1101/2020.05.15.098988

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