Article

MethNet: a robust approach to identify regulatory hubs and their distal targets in cancer

2023-07-10

Abstract excerpt

Aberrations in the capacity of DNA/chromatin modifiers and transcription factors to bind non-coding regions can lead to changes in gene regulation and impact disease phenotypes. However, identifying distal regulatory elements and connecting them with their target genes remains challenging. Here, we present MethNet, a pipeline that integrates large-scale DNA methylation and gene expression data across multiple canc...

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Literature Corpus work: 8a8d5c42-f474-59ab-a221-cc69be68468e
DOI: 10.1101/2023.07.07.548142

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