Article

Non-coding loci without epigenomic signals can be essential for maintaining global chromatin organization and cell viability

2020-12-14

Abstract excerpt

<h4>ABSTRACT</h4> The majority of the non-coding regions in the human genome do not harbor any annotated element and are even not marked with any epigenomic signal or protein binding. An understudied aspect of these regions is their possible roles in stabilizing the 3D chromatin organization. To illuminate their “structural importance”, we chose to start with the non-coding regions forming many 3D contacts (refer...

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Literature Corpus work: 7ae88ce3-c427-5317-9ef0-a5d5ea6f2f96
DOI: 10.1101/2020.12.13.422541

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