Article

Candidate cancer driver mutations in superenhancers and long-range chromatin interaction networks

2017-12-19

Abstract excerpt

A comprehensive catalogue of the mutations that drive tumorigenesis and progression is essential to understanding tumor biology and developing therapies. Protein-coding driver mutations have been well-characterized by large exome-sequencing studies, however many tumors have no mutations in protein-coding driver genes. Non-coding mutations are thought to explain many of these cases, however few non-coding drivers b...

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Literature Corpus work: c7ea03ed-4d26-58d3-8611-00155766ab89
DOI: 10.1101/236802

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