Article

Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction

2023-11-08

Abstract excerpt

<title>Abstract</title> <p>Tauopathies encompass a range of neurodegenerative disorders, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). Unfortunately, current treatment approaches for tauopathies have yielded limited success, underscoring the pressing need for novel therapeutic strategies. We observed distinct signatures of impaired glycogen metabolism in the <italic>Drosophila </italic>brain...

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Literature Corpus work: a264bab1-59c7-5083-b1b5-d3450ef69e4d
DOI: 10.21203/rs.3.rs-3526342/v1

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