Article

A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer’s disease models

2023-06-26

Abstract excerpt

Brains are highly metabolically active organs, consuming 20% of an organisms’ energy at resting state. A decline in glucose metabolism is a common feature across a number of neurodegenerative diseases. Another common feature is the progressive accumulation of insoluble protein deposits, it’s unclear if the two are linked. Glucose metabolism in the brain is highly coupled between neurons and glia, with glucose take...

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Literature Corpus work: 3a1e9343-ab77-5e65-99a1-9c0b52aadba7
DOI: 10.1101/2023.06.25.546435

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