Article

Ancestry-specific and multi-ancestry genome-wide association studies of restless legs syndrome

2026-04-29

Abstract excerpt

Restless legs syndrome (RLS) is a common neurological disorder that disrupts sleep and quality of life, yet its genetics has been examined almost exclusively in individuals of European ancestry. We performed genome-wide association analyses of RLS in African (2,176 cases; 153,313 controls), Latin American (2,024 cases; 91,902 controls), and European (36,993 cases; 639,182 controls) ancestry groups, followed by a m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a20e1931-877b-539f-8b7c-0e2c666b6b03
DOI: 10.64898/2026.04.28.26351960

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Ancestry-specific and multi-ancestry genome-wide association studies of restless legs syndromeDOI 10.64898/2026.04.28.26351960Read

Large-scale genome- and phenome-wide analyses reveal the genetic architecture, pathophysiology and comorbidity of restless legs syndromeSemantic proximity Read

Genomic analysis identifies risk factors in restless legs syndromeSemantic proximity Read

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.Semantic proximity Read

Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.Semantic proximity Read

Replication of restless legs syndrome loci in three European populations.Semantic proximity Read

Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.Semantic proximity Read

Genomewide linkage scan identifies a novel susceptibility locus for restless legs syndrome on chromosome 9p.Semantic proximity Read

Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome.Semantic proximity Read

Genetics of restless legs syndrome.Semantic proximity Read

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.Semantic proximity Read

Restless legs syndrome: an update on genetics and future perspectives.Semantic proximity Read

Reassessment of candidate gene studies for idiopathic restless legs syndrome in a large genome-wide association study dataset of European ancestry.Semantic proximity Read