Article
Restless legs syndrome: an update on genetics and future perspectives.
Clinical genetics - 1 Apr 2008
Pichler I, Hicks A A, Pramstaller P P
Abstract excerpt
Restless legs syndrome (RLS) is a common, underdiagnosed neurological condition with an age-dependent prevalence of up to 14%. Familial aggregation has been widely shown since Ekbom's first description of the disorder in 1945. Five loci (12q, 14q, 9p, 2q, and 20p) have been described so far, although no positive association with any specific genes, either within these loci or additional candidates investigated,...
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