Article
Replication of restless legs syndrome loci in three European populations.
Journal of medical genetics - 1 May 2009
Kemlink D, Polo O, Frauscher B, Gschliesser V, Högl B, Poewe W, Vodicka P, Vavrova J, Sonka K, Nevsimalova S, Schormair B, Lichtner P, Silander K, Peltonen L, Gieger C, Wichmann H E, Zimprich A, Roeske D, Müller-Myhsok B, Meitinger T, Winkelmann J
Abstract excerpt
BACKGROUND: Restless legs syndrome (RLS) is associated with common variants in three intronic and intergenic regions in MEIS1, BTBD9, and MAP2K5/LBXCOR1 on chromosomes 2p, 6p and 15q. METHODS: Our study investigated these variants in 649 RLS patients and 1230 controls from the Czech Republic (290 cases and 450 controls), Austria (269 cases and 611 controls) and Finland (90 cases and 169 controls). Ten single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
