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Article

Genomic Analysis Identifies Risk Factors in Restless Legs Syndrome.

Annals of neurology - 1 Nov 2024

Akçimen Fulya, Chia Ruth, Saez-Atienzar Sara, Ruffo Paola, Rasheed Memoona, Ross Jay P, Liao Calwing, Ray Anindita, Dion Patrick A, Scholz Sonja W, Rouleau Guy A, Traynor Bryan J

Abstract excerpt

OBJECTIVE: Restless legs syndrome (RLS) is a neurological condition that causes uncomfortable sensations in the legs and an irresistible urge to move them, typically during periods of rest. The genetic basis and pathophysiology of RLS are incompletely understood. We sought to identify additional novel genetic risk factors associated with RLS susceptibility. METHODS: We performed a whole-genome sequencing and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39078117
DOI: 10.1002/ana.27040
PMCID: PMC11496024

Genes

GLO1
LMX1B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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