Article

CRISPR/Cas9-based somatic knock-in of reporters in the avian embryo in ovo

2024-10-12

Abstract excerpt

Gene editing and protein tagging are at the heart of modern developmental and cell biology. The advent of CRISPR/Cas9 based methods offers the possibility to develop customized approaches for genomic manipulations in non-classical experimental models. Here, we show that highly efficient somatic knock-ins of long DNA fragments can be achieved in the developing chick neural tube in ovo. We compare different types of...

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Literature Corpus work: a1a9564e-c76f-560a-aa17-3d9526357e83
DOI: 10.1101/2024.10.10.617291

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