Article

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for <i>Sptbn2</i> in neurulation and abdominal wall closure

2020-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Gene variants associated with disease are efficiently identified with whole genome sequencing or GWAS, but validation in vivo lags behind. We developed NEPTUNE ( ne ural p late targeting by in u tero n anoinj e ction), to rapidly and flexibly introduce gene expression-modifying viruses to the embryonic murine neural plate prior to neurulation, to target the future adult nervous system. Sta...

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Literature Corpus work: 5b70ea8c-5be9-5128-a034-daa76770009b
DOI: 10.1101/2020.05.28.115972

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Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for <i>Sptbn2</i> in neurulation and abdominal wall closureDOI 10.1101/2020.05.28.115972Read

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