Article

Uncertainty-aware quantitative analysis of the structure and dynamics of T cell receptor repertoires

2026-07-01

Abstract excerpt

Diversity and dynamics of immune cell receptor repertoires (IRRs) are two factors at the functional heart of adaptive immunity that together make IRRs difficult to grasp. Moreover, measurements are compounded by various sources of experimental noise. Here we propose a computational framework ( ClustIRR ) for uncertainty-aware quantitative analysis of IRR structure and dynamics. ClustIRR maps multiple IRRs across...

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Literature Corpus work: 9f64dab3-ef89-5a74-a207-e25d725ab486
DOI: 10.64898/2026.06.28.735097

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