Article

UnivAIRRse: A Unified Framework for Organizing and Comparing Adaptive Immune Receptor Repertoire Simulators

2026-02-19

Abstract excerpt

Adaptive immune receptor repertoire sequencing (AIRR-seq) enables large-scale profiling of B- and T-cell receptor diversity and has become a cornerstone of modern computational immunology. However, AIRR-seq provides only a partial and lossy molecular snapshot of immune dynamics, lacking explicit ground truth for clonal ancestry, lineage trajectories, antigen specificity, and longitudinal immune evolution. This lim...

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Literature Corpus work: fa0a4358-75e6-53df-8b18-9f612748b30a
DOI: 10.64898/2026.02.19.706510

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