Article

Quantifying lymphocyte receptor diversity

2016-04-03

Abstract excerpt

To recognize pathogens, B and T lymphocytes are endowed with a wide repertoire of receptors generated stochastically by V(D)J recombination. Measuring and estimating the diversity of these receptors is of great importance for understanding adaptive immunity. In this chapter we review recent modeling approaches for analyzing receptor diversity from high-throughput sequencing data. We first clarify the various exist...

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Literature Corpus work: bfcf1256-ea39-525a-8cd0-5d82252188f8
DOI: 10.1101/046870

Open publication

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