Article
The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires.
BMC bioinformatics - 7 Mar 2017
Bolen Christopher R, Rubelt Florian, Vander Heiden Jason A, Davis Mark M
Abstract excerpt
BACKGROUND: The B and T cells of the human adaptive immune system leverage a highly diverse repertoire of antigen-specific receptors to protect the human body from pathogens. The sequencing and analysis of immune repertoires is emerging as an important tool to understand immune responses, whether beneficial or harmful (in the case of autoimmunity). However, methods for studying these repertoires, and for directly...
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