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Article

Immune Regulation in Time and Space: The Role of Local- and Long-Range Genomic Interactions in Regulating Immune Responses.

Frontiers in immunology - 1 Jan 2021

Devenish Liam P, Mhlanga Musa M, Negishi Yutaka

Abstract excerpt

Mammals face and overcome an onslaught of endogenous and exogenous challenges in order to survive. Typical immune cells and barrier cells, such as epithelia, must respond rapidly and effectively to encountered pathogens and aberrant cells to prevent invasion and eliminate pathogenic species before they become overgrown and cause harm. On the other hand, inappropriate initiation and failed termination of immune...

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Identifiers

PMID: 34046034
DOI: 10.3389/fimmu.2021.662565
PMCID: PMC8144502

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