Article

Modeling Global Genomic Instability in Chronic Myeloid Leukemia (CML) using patient-derived induced pluripotent stem cells (iPSC)

2022-09-12

Abstract excerpt

<h4>ABSTRACT</h4> Using induced Pluripotent Stem Cell (iPSC) technology, it is now possible to reprogram the primary leukemic cells to pluripotency and generate a major source of stem cells. To determine the feasibility of modeling global genomic instability characterizing chronic myeloid leukemia (CML) progression towards blast crisis (BC), we have used a patient-specific iPSC line that has been submitted to in...

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Literature Corpus work: 9eb93e94-d63b-5e02-b5a0-f8b3292e07c9
DOI: 10.1101/2022.09.09.505857

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