Article

GUIDE deconstructs genetic architectures using association studies

2024-05-06

Abstract excerpt

Genome-wide association studies have revealed that the genetic architecture of most complex traits is characterized by a large number of distinct effects scattered across the genome. Functional enrichment analyses help provide some biological interpretation of associated variants but more work is needed to further translate GWAS hits into meaningful biological insights. Thus, we set out to leverage the genetic ass...

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Literature Corpus work: 9e98d537-8cb7-5cf1-bc94-e73b19880a29
DOI: 10.1101/2024.05.03.592285

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